Previous research has shown that vitamin D deficiency can increase the risk of multiple sclerosis (EM), and a new study suggests that complementing it into high doses could help reduce symptoms.
The study included 303 adults in France who had experienced clinically isolated syndrome (CIS), which is a single initial period of neurological symptoms that could lead to EM, in the last 90 days.
A group of participants took high doses (100,000 IU) from collector (vitamin D3) every two weeks for 24 months.
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Among that group, 60.3% experienced a relapse of new or enlarged symptoms or injuries in magnetic resonance scans.
A group of participants took high doses (100,000 IU) from collector (vitamin D3) every two weeks for 24 months. (Istock)
In comparison, 74.1% of those who took a placebo experienced those same effects, which is a “statistically significant difference,” the researchers wrote, which were Chu Nîmes, University Montpellier and multiple sclerosis centers in France.
The findings of the double -blind random study were published in the Jama magazine.
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“The Oral Collector 100, 000 IU every two weeks significantly reduced the activity of the disease at the CEI and the EM Early recurring EM,” the researchers wrote.
“These results justify greater research, including the potential role of vitamin D high pulse dose as additional therapy.”
Among the patients who took vitamin D supplements, 60.3% experienced a relapse of new or enlarged symptoms or injuries in magnetic resonance scans, less than those who did not take it. (Istock)
Bruce Bebo, Executive Vice President of Research of the National Society of MS in Oregon, did not participate in the investigation, but told Fox News Digital about what he described as a “well -designed study.”
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“These findings suggest that the high dose of vitamin D can be a promising approach to reduce the activity of the disease in the early stages of EM,” he said.
However, the studies published above could not link supplementation with vitamin D with a reduced activity of EM disease, although they used lower doses, according to Bebo.
“The Oral Collector 100, 000 IU every two weeks significantly reduced the activity of the disease at the CEI and the EM Early recurring EM,” the researchers wrote. (Istock)
“In general, the evidence suggests that the effects of supplementation with vitamin D are probably modest, they will require high doses and will be more effective when they are taken early in the course of the disease by people deficient vitamin D,” he said.
The American Academy of Neurology currently recommends a range of 300 to 4,000 units per day for an adult, with 4,000 units as the most recommended dose by most health authorities, said Bebo.
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“It is important to keep in mind that Jama’s study used a significantly higher dose (100,000 units per day). Although they did not report any adverse event, excessive vitamin D intake can be toxic,” he warned.
“High doses can cause excess of calcium in the blood that leads to nausea, vomiting, weakness, frequent urination and, in some cases, renal damage.
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Any person who is interested in supplementation with vitamin D should discuss it with a neurologist or health care provider to determine the best approach, he recommended.
